姓名：吴坚
职称：副研究员
个人简介：江苏南通人，博士。
专业研究领域：基础医学、组织工程、神经与神经再生研究。
专著与论集：
1. Jian Wu, Zhen-Yu Zhu, Zhi-Wei Fan, Ying Chen, Ri-Yun Yang, Yi Li. Downregulation of EphB2 by RNA interference attenuates glial/fibrotic scar formation and promotes axon growth. Neural Regen Res. 2022 Feb;17(2):362-369. doi: 10.4103/1673-5374.317988.
2. Jian Wu, Bing Lu, Riyun Yang, Ying Chen, Xue Chen, Yi Li. EphB2 knockdown decreases the formation of astroglial-fibrotic scars to promote nerve regeneration after spinal cord injury in rats. CNS Neurosci Ther. 2021 Jun;27(6):714-724. doi:10.1111/cns.13641. Epub 2021 Apr 1.
3. Xue Chen#, Jian Wu#, Rongcheng Sun, Yahong Zhao, Yi Li, Jingying Pan, Ying Chen, Xiaodong Wang. Tubular scaffold with microchannels and an H-shaped lumen loaded with bone marrow stromal cells promotes neuroregeneration and inhibits apoptosis after spinal cord injury. J Tissue Eng Regen Med. 2020 Mar;14(3):397-411. doi: 10.1002/term.2996. Epub 2020 Jan 29.
4. Wu J#, Zhao R#, Guo L, Zhen X. Morphine-induced inhibition of Ca2+ -dependent d-serine release from astrocytes suppresses excitability of GABAergic neurons in the nucleus accumbens. Addict Biol. 2017 Sep;22(5):1289-1303. Epub 2016 May 29.
5. Ding F#, Wu J#, Yang Y, Hu W, Zhu Q, Tang X, Liu J, Gu X. Use of tissue-engineered nerve grafts consisting of a chitosan/poly(lactic-co-glycolic acid)-based scaffold included with bone marrow mesenchymal cells for bridging 50-mm dog sciatic nerve gaps. Tissue Eng Part A. 2010 Dec;16(12):3779-90.
主要科研项目
无
讲授课程
组织学与胚胎学（本科生）、生物光镜标本技术（硕士研究生）
指导研究生情况
无
