姓名：尹晓敏
职称：副教授
个人简介：江苏南通人，医学博士。
专业研究领域：神经退行性疾病的机制研究。
专著与论集：
1. Yin X, Li Y, Fan X, Huang F, Qiu Y, Zhao C, Zhou Z, Gu Q, Xia L, Bao J, Wang X, Liu F, Qian W. SIRT1 deficiency increases O-GlcNAcylation of tau, mediating synaptic tauopathy. Mol Psychiatry. 2022;27(10):4323-4334.
2. Yin X, Zhao C, Qiu Y, Zhou Z, Bao J, Qian W. Dendritic/Post-synaptic Tau and Early Pathology of Alzheimer's Disease. Front Mol Neurosci. 2021;14:671779.
3. Yin X, Zhou Z, Qiu Y, et al. SIRT1 Regulates Tau Expression and Tau Synaptic Pathology. J Alzheimers Dis. 2021;84(2):895-904.
4. Yin X, Jiang X, Wang J, et al. SIRT1 Deacetylates SC35 and Suppresses Its Function in Tau Exon 10 Inclusion. J Alzheimers Dis. 2018;61(2):561-570.
5. Yin X, Jin N, Shi J, et al. Dyrk1A overexpression leads to increase of 3R-tau expression and cognitive deficits in Ts65Dn Down syndrome mice. Sci Rep. 2017;7(1):619.
6. Yin X, Jin N, Gu J, et al. Dual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A) modulates serine/arginine-rich protein 55 (SRp55)-promoted Tau exon 10 inclusion. J Biol Chem. 2012;287(36):30497-30506.
主要科研项目
主持国家自然科学基金项目1项，江苏省高校自然科学基金1项。
讲授课程
生物化学与分子生物学
指导研究生情况
