姓名:胡宝英
职称:副教授
个人简介:浙江绍兴人,理学博士。
专业研究领域:基础医学、肿瘤免疫微环境。
专著与论集:
1. Xingchao Wang, Jianfeng Zhang, Baoying Hu#, Fei Qian. High Expression of CSF-1R Predicts Poor Prognosis and CSF-1Rhigh Tumor-Associated Macrophages Inhibit Anti-Tumor Immunity in Colon Adenocarcinoma. Front Oncol[J]. 2022 Apr 4;12:850767.
2. Chen Gong*, Baoying Hu*, Haifeng Chen, Jianxin Zhu, Jinshan Nie, Lu Hua, Long Chen, Yanfei Fang, Cheng Hang, Ye Lu. β2-adrenergic receptor drives the metastasis and invasion of pancreatic ductal adenocarcinoma through activating Cdc42 signaling pathway. J Mol Histol[J]. 2022 Aug;53(4):645-655.
3. Lu Hua, Daliang Yan, Chunhua Wan, Baoying Hu#. Nucleolus and Nucleolar Stress: From Cell Fate Decision to Disease Development. Cells. 2022 Sep 27;11(19):3017.
4. Xudong He*, Yun Gu*, Yifan Cao*, Baoying Hu*, Hanji Fang, Yuchao Fei, Kunpeng Lv, Xin Liu, Jieti Wang, Chao Lin, Hao Liu, Heng Zhang, He Li, Ruochen Li, Hongyong He, Jiejie Xu. Impact of intratumoural CD73 expression on prognosis and therapeutic response in patients with gastric cancer. Eur J Cancer. 2021 Nov;157:114-123.
5. Hu B, Wang Z, Zeng H, Qi Y, Chen Y, Wang T, Wang J, Chang Y, Bai Q, Xia Y, Wang Y, Liu L, Zhu Y, Dai B, Guo J, Xu L, Zhang W, Xu J. Blockade of DC-SIGN + Tumor-Associated Macrophages Reactivates Antitumor Immunity and Improves Immunotherapy in Muscle-Invasive Bladder Cancer. Cancer Research. 2020 Apr 15;80(8):1707-1719.
6. Hu B*, Hua L, Ni W, Wu M, Yan D, Chen Y, Lu C, Chen B, Wan C. Nucleostemin/GNL3 promotes nucleolar polyubiquitylation of p27kip1 to drive hepatocellular carcinoma progression. Cancer Lett. 2017 Mar 1;388:220-229.
7. Hua L*, Hu B*, Yan D, Liu J, Shen Y, Zhao F, Shen C, Chen B, Cui X. Upregulated expression of Nucleostemin/GNL3 is associated with poor prognosis and Sorafenib Resistance in Hepatocellular Carcinoma. Pathol Res Pract. 2017 Jun;213(6):688-697 (* co-first author).
主要科研项目
主持多项省部级以上科研项目,其中包括国家自然科学基金项目2项,江苏省高等学校自然科学基金1项,南通市科技局项目3项。
讲授课程
医学免疫学