黄中伟

发布时间:2023-07-24录入员:

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姓名:黄中伟

职称:教授、主任医师

个人简介:江苏南通人,博士生导师

专业研究领域:急诊医学(脓毒症、重症急性胰腺炎、多脏器功能衰竭、心肺复苏等)

专著与论集:

1.        Qi L, Yan Y, Chen B, Cao J, Liang G, Xu P, Wang Y, Ren Y, Mao G, Huang Z, Xu C, Jiang H. Research progress of circRNA as a biomarker of sepsis: a narrative review. Ann Transl Med. 2021 Apr;9(8):720. doi: 10.21037/atm-21-1247. PMID: 33987418; PMCID: PMC8106021.

2.        Yan Y, Li M, Lin J, Ji Y, Wang K, Yan D, Shen Y, Wang W, Huang Z, Jiang H, Sun H, Qi L. Adenosine monophosphate activated protein kinase contributes to skeletal muscle health through the control of mitochondrial function. Front Pharmacol. 2022 Oct 20;13:947387. doi: 10.3389/fphar.2022.947387. PMID: 36339617; PMCID: PMC9632297.

3.        Zhang X, Huang Z, Wang Y, Wang T, Li J, Xi P. Long Non-Coding RNA RMRP Contributes to Sepsis-Induced Acute Kidney Injury. Yonsei Med J. 2021 Mar;62(3):262-273. doi: 10.3349/ymj.2021.62.3.262. PMID: 33635017; PMCID: PMC7934096.

4.        Liang G, Wu Y, Guan Y, Dong Y, Jiang L, Mao G, Wu R, Huang Z, Jiang H, Qi L, Tang J. The correlations between the serum expression of miR-206 and the severity and prognosis of sepsis. Ann Palliat Med. 2020 Sep;9(5):3222-3234. doi: 10.21037/apm-20-1391. Epub 2020 Sep 3. PMID: 32921119.

5.        Liu Y, Sun R, Jiang H, Liang G, Huang Z, Qi L, Lu J. Development and validation of a predictive model for in-hospital mortality in patients with sepsis-associated liver injury. Ann Transl Med. 2022 Sep;10(18):997. doi: 10.21037/atm-22-4319. PMID: 36267798; PMCID: PMC9577780.

6.        Jiang H, Dong Y, Yan D, Wu Y, Wang Y, Ren Y, Mao G, Liang G, Liu W, Zhou Y, Huang Z, Qi L. The expression of STEAP4 in peripheral blood predicts the outcome of septic patients. Ann Transl Med. 2021 Oct;9(20):1519. doi: 10.21037/atm-21-2794. PMID: 34790725; PMCID: PMC8576732.

7.        Qi L, Wu Y, Li M, Xu C, Mao G, Liang G, Dong Y, Yan D, Yan Y, Huang Z, Sun K, Jiang H. G-rich sequence factor 1 serves as a prognostic biomarker in septic patients. Ann Transl Med. 2021 Apr;9(8):691. doi: 10.21037/atm-21-1022. PMID: 33987389; PMCID: PMC8106065.

8.        Xue YZ, Wu TL, Dai YY, Sheng YY, Wu YM, Xia BL, Huang ZW. NEDD9 expression is correlated with epithelial-to-mesenchymal transition markers in colorectal cancer. Int J Clin Exp Pathol. 2017 Aug 1;10(8):8640-8646. PMID: 31966721; PMCID: PMC6965374.

9.        Liang G, Wu R, Jiang L, Liu Y, Mao G, Huang Z, Qi L, Jiang H. The role of lipoprotein-associated phospholipase A2 in acute kidney injury of septic mice. Transl Androl Urol. 2020 Oct;9(5):2192-2199. doi: 10.21037/tau-20-1173. PMID: 33209683; PMCID: PMC7658152.

10.     Zhang D, Cai Y, Chen M, Gao L, Shen Y, Huang Z. OGT-mediated O-GlcNAcylation promotes NF-κB activation and inflammation in acute pancreatitis. Inflamm Res. 2015 Dec;64(12):943-52. doi: 10.1007/s00011-015-0877-y. Epub 2015 Sep 25. PMID: 26407569.

11.     Sun R, Wang X, Jiang H, Yan Y, Dong Y, Yan W, Luo X, Miu H, Qi L, Huang Z. Prediction of 30-day mortality in heart failure patients with hypoxic hepatitis: Development and external validation of an interpretable machine learning model. Front Cardiovasc Med. 2022 Oct 28;9:1035675. doi: 10.3389/fcvm.2022.1035675. PMID: 36386374; PMCID: PMC9649827.

12.     Cai Q, Huang Z, Qi L, Wang T, Shen Y, Huang J. Tazarotene-induced gene 2 is associated with poor survival in non-small cell lung cancer. Oncol Lett. 2016 Oct;12(4):2680-2685. doi: 10.3892/ol.2016.5025. Epub 2016 Aug 16. PMID: 27698842; PMCID: PMC5038457.

13.     Xu P, Mao G, Jiang H, Ren Y, Wang Y, Liang G, Liu W, Zhou Y, Huang Z, Zhang B, Chen X, Qi L. Analysis of the epidemiological and clinical characteristics of 65 patients with scrub typhus on the east coast of China. Ann Palliat Med. 2021 May;10(5):5694-5705. doi: 10.21037/apm-21-1100. PMID: 34107715.

14.     Qi L, Wu Y, Shan L, Dong Y, Mao G, Liang G, Gong H, Xu C, Jiang H, Huang Z. A clinical study of preoperative carbohydrate administration to improve insulin resistance in patients with multiple injuries. Ann Palliat Med. 2020 Sep;9(5):3278-3287. doi: 10.21037/apm-20-1424. Epub 2020 Sep 10. PMID: 32921117.

15.     Cai Y, Shen Y, Xu G, Tao R, Yuan W, Huang Z, Zhang D. TRAM1 protects AR42J cells from caerulein-induced acute pancreatitis through ER stress-apoptosis pathway. In Vitro Cell Dev Biol Anim. 2016 May;52(5):530-6. doi: 10.1007/s11626-016-0011-7. Epub 2016 Apr 22. PMID: 27105999.

16.     Jiang H, Xi Q, Wang F, Sun Z, Huang Z, Qi L. Increased expression of neuropilin 1 is associated with epithelial ovarian carcinoma. Mol Med Rep. 2015 Aug;12(2):2114-20. doi: 10.3892/mmr.2015.3580. Epub 2015 Apr 1. PMID: 25845525.

17.     Jiang H, Ren Y, Qi G, Wang Y, Xu C, Mao G, Liang G, Yan D, Yan Y, Dong Y, Huang Z, Qi L. The effect of HES130/0.4 sodium chloride solution on kidney function following early fluid resuscitation in shock patients. Transl Androl Urol. 2021 Nov;10(11):4288-4297. doi: 10.21037/tau-21-972. PMID: 34984193; PMCID: PMC8661255.

18.     Huang Z, Jiang H, Cui X, Liang G, Chen Y, Wang T, Sun Z, Qi L. Elevated serum levels of lipoproteinassociated phospholipase A2 predict mortality rates in patients with sepsis. Mol Med Rep. 2018 Jan;17(1):1791-1798. doi: 10.3892/mmr.2017.8034. Epub 2017 Nov 13. PMID: 29138849.

19.     Qi L, Wang Y, Chen B, Ren Y, Mao G, Liang G, Liu W, Zhou Y, Huang Z, Sun K, Jiang H. In vitro bacteriostatic effects of Polymyxin B combined with Propofol medium and long chain fat emulsion injection against Escherichia coli. Ann Palliat Med. 2021 Apr;10(4):4687-4696. doi: 10.21037/apm-21-751. PMID: 33966417.

20.     Cai Y, Shen Y, Gao L, Chen M, Xiao M, Huang Z, Zhang D. Karyopherin Alpha 2 Promotes the Inflammatory Response in Rat Pancreatic Acinar Cells Via Facilitating NF-κB Activation. Dig Dis Sci. 2016 Mar;61(3):747-57. doi: 10.1007/s10620-015-3948-6. Epub 2015 Nov 2. PMID: 26526450.

21.     Jiang H, Qi L, Wang F, Sun Z, Huang Z, Xi Q. Decreased semaphorin 3A expression is associated with a poor prognosis in patients with epithelial ovarian carcinoma. Int J Mol Med. 2015 May;35(5):1374-80. doi: 10.3892/ijmm.2015.2142. Epub 2015 Mar 17. PMID: 25812535.

22.     Qi L, Jiang H, Cui X, Liang G, Gao M, Huang Z, Xi Q. Synthesis of methylprednisolone loaded ibuprofen modified dextran based nanoparticles and their application for drug delivery in acute spinal cord injury. Oncotarget. 2017 Sep 5;8(59):99666-99680. doi: 10.18632/oncotarget.20649. PMID: 29245932; PMCID: PMC5725123.

23.     Shen Y, Jiang D, Wang T, Li M, Wang Y, Li J, Yan H, Yuan M, Ji Y, Shen Y, Yuan D, Huang Z. Blocking vicious cycle of cardiac dysfunction by external cardiopulmonary resuscitation is the key to rescue acute aluminium phosphide poisoning. Perfusion. 2023 Jan;38(1):214-219. doi: 10.1177/02676591211046868. Epub 2021 Oct 7. PMID: 34617832.

24.     Li A, Li J, Bao Y, Yuan D, Huang Z. Xuebijing injection alleviates cytokine-induced inflammatory liver injury in CLP-induced septic rats through induction of suppressor of cytokine signaling 1. Exp Ther Med. 2016 Sep;12(3):1531-1536. doi: 10.3892/etm.2016.3476. Epub 2016 Jun 24. PMID: 27602076; PMCID: PMC4998358.

25.     Jiang MH, Su YM, Tang JZ, Shen YB, Deng XT, Yuan DS, Wu J, Pan M, Huang ZW. Angiotensin-converting enzyme gene 2350 G/A polymorphism and susceptibility to atrial fibrillation in Han Chinese patients with essential hypertension. Clinics (Sao Paulo). 2013 Nov;68(11):1428-32. doi: 10.6061/clinics/2013(11)08. PMID: 24270955; PMCID: PMC3812555.

26.     Jiang D, Bian T, Shen Y, Huang Z. Association between admission systemic immune-inflammation index and mortality in critically ill patients with sepsis: a retrospective cohort study based on MIMIC-IV database. Clin Exp Med. 2023 Mar 17:110. doi: 10.1007/s10238-023-01029-w. Epub ahead of print. PMID: 36930382; PMCID: PMC10022570.

27.     Huang ZW, Tang JZ, Chen Y, Yuan DS, Shen YB, Wang W. [Protective effect of reduced glutathione on multiple organ function in patient with acute pancreatitis]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2005 Nov;17(11):673-4. Chinese. PMID: 16297323.

部分中文文章:

28.     李晶菁,姜岱山,张霞,陈瑜,黄中伟.入院时血糖水平与脓毒症患者预后的相关性研究[J].实用临床医药杂志,2023,27(05):104-109.

29.     蔡丹磊,倪凯华,韩毓,黄中伟,董岩松.外周血滤泡辅助性T细胞表达与哮喘患者病情的相关性[J].中外医学研究,2022,20(33):64-67.DOI:10.14033/j.cnki.cfmr.2022.33.016.

30.     燕雯霄,蒋海燕,梁桂文,丁俊华,缪华,倪红兵,黄中伟,祁雷.突发公共卫生事件背景下加强青少年急救知识科普工作的探讨[J].中国急救复苏与灾害医学杂志,2022,17(10):1381-1384.

31.     沈艳,姜岱山,李梦秋,王菲,王萌,周忠霞,仇惠芫,王亚运,王辉,李晶菁,王霆,蔡丹磊,袁鼎山,沈雁波,黄中伟.肾脏超声对多发伤患者急性肾损伤的早期预警价值[J].重庆医科大学学报,2022,47(10):1215-1219.DOI:10.13406/j.cnki.cyxb.003107.

32.     沈艳,李伟,王艳,黄中伟.人工智能在急诊危重症教学中的应用体会[J].教育教学论坛,2022(37):69-72.

33.     缪华,蒋海燕,梁桂文,丁俊华,燕雯霄,黄中伟,祁雷.新冠疫情常态化防控背景下县级医院急诊急救现实状况和发展思路[J].交通医学,2022,36(03):329-330.DOI:10.19767/j.cnki.32-1412.2022.03.035.

34.     刘园园,季楠,蒋海燕,梁桂文,黄中伟,祁雷.以东部沿海某县级市为例作突发公共卫生事件应急体系建设情况分析[J].中国急救复苏与灾害医学杂志,2022,17(01):46-48+52.

35.     袁磊,黄中伟.连续性肾脏替代治疗对急性肾损伤患者肾功能及预后的影响[J].基层医学论坛,2021,25(28):4076-4078.DOI:10.19435/j.1672-1721.2021.28.034.

36.     钱骏,黄中伟,徐建如,陆仁飞,王海燕.sEPCR在脓毒症患者中的表达及临床意义[J].中国医药导报,2021,18(10):88-91.

37.     丁霞,黄中伟.全生命周期的健康管理对老年慢性阻塞性肺疾病患者肺功能的影响[J].中国老年学杂志,2021,41(01):53-56.

38.     祁雷,吴瑶,董岩松,蒋岚,梁桂文,蒋海燕,吴若,毛国敏,黄中伟.突发公共卫生事件背景下高校急诊急救知识教学策略和模式探讨[J].交通医学,2020,34(06):658-659.DOI:10.19767/j.cnki.32-1412.2020.06.033.

39.     蔡丹磊,黄中伟,包玉华,姜岱山,王亚运.慢性阻塞性肺疾病合并肺部感染患者 TGF-β1/Smads信号通路的表达[J].中华医院感染学杂志,2020,30(21):3253-3257.

40.     吴小燕,黄中伟,董岩松,吴瑶,蒋海燕,祁雷.老年脓毒症患者血浆爱帕琳肽水平与心肌损伤的相关性[J].中国老年学杂志,2020,40(11):2372-2375.

41.     沈艳,李伟,姜岱山,王艳,王萌,王辉,沈雁波,黄中伟.大数据时代背景下急诊重症教学模式改革初步实践[J].教育教学论坛,2020(02):160-162.

42.     徐程,梁桂文,蒋海燕,丁俊华,黄中伟,祁雷.床旁肺超声在肺部感染灶解剖定位及大小判断中的应用[J].解剖学报,2019,50(06):786-790.DOI:10.16098/j.issn.0529-1356.2019.06.015.

43.     蒋伟,张健锋,李山峰,姜岱山,黄中伟.血清细胞黏附分子对脓毒症急性肾损伤的预测价值研究[J].中国全科医学,2020,23(20):2525-2529.

44.     陈小燕,黄中伟.失效模式与效应分析法对护理差错事故防范的影响[J].西部中医药,2018,31(08):134-136.

45.     陈小燕,黄中伟,崔秋霞,吉云兰,单君.早期目标导向干预对老年严重脓毒症患者功能改善及生存率的影响研究[J].中国全科医学,2018,21(32):3946-3950.

46.     陈小燕,黄中伟.失效模式和效应分析模式对儿童急诊静脉留置针患者应用成效及安全性分析[J].西部中医药,2018,31(07):105-108.

47.     蔡丹磊,黄中伟,蔡琦,王霆,姜岱山.左氧氟沙星联合舒利迭对慢性阻塞性肺疾病急性加重期患者血清SAATGF-β1copeptinsICAM-1水平的影响[J].现代生物医学进展,2018,18(04):709-712+717.DOI:10.13241/j.cnki.pmb.2018.04.023.

48.     徐程,黄中伟,蒋海燕,顾玉慧,袁鼎山,祁雷.床旁超声引导下幽门定位及其在鼻空肠管置入术中的应用[J].解剖学报,2017,48(04):440-444.DOI:10.16098/j.issn.0529-1356.2017.04.012.

49.     袁晓宇,黄中伟.心肌型脂肪酸结合蛋白在超急性期冠心病急性心肌梗死中的诊断及应用价值[J].南通大学学报(医学版),2016,36(06):525-528.DOI:10.16424/j.cnki.cn32-1807/r.2016.06.005.

50.     丁剑锋,黄中伟,徐红梅.损伤控制性手术治疗肝破裂出血的临床效果观察[J].中国医学前沿杂志(电子版),2016,8(10):83-86.

51.     黄中伟,祁雷,蒋海燕.急诊科规范化教学查房的实践与思考[J].交通医学,2016,30(02):200-202.

52.     丁俊华,黄中伟,沈雁波,王霆.老年危重症患者心力衰竭特征及其危险因素分析[J].临床急诊杂志,2015,16(11):871-874.DOI:10.13201/j.issn.1009-5918.2015.11.015.

53.     王霆,黄中伟,沈雁波,祁雷,蔡琦.PPAR-γ配体对大鼠脓毒症急性肺损伤的保护作用[J].江苏医药,2012,38(18):2131-2133+2233.DOI:10.19460/j.cnki.0253-3685.2012.18.008.

54.     陈瑜,黄中伟,沈雁波.SP-A在急性坏死性胰腺炎肺损伤大鼠的表达和意义[J].重庆医学,2011,40(25):2497-2498+2492+2603.

55.     陈瑜,黄中伟,沈雁波.盐酸戊乙奎醚对急性坏死性胰腺炎肺损伤大鼠HMGBISP-A表达的影响[J].交通医学,2011,25(04):337-340.

56.     陈瑜,黄中伟,沈雁波.急性坏死性胰腺炎肺损伤大鼠高迁移率族蛋白B1的表达及意义[J].交通医学,2010,24(05):483-485.

57.     王霆,黄中伟,沈雁波.地塞米松联合水溶性维生素治疗双硫仑样反应36[J].交通医学,2010,24(05):511+513.

58.     王辉,黄中伟,王霆.纳络酮联合醒脑静治疗急性酒精中毒昏睡期效果观察[J].交通医学,2010,24(04):412+414.

59.     袁鼎山,黄中伟,沈雁波,李军,薛育政,陈瑜.胰蛋白酶原激活肽和降钙素原早期诊断重症急性胰腺炎的价值[J].南通大学学报(医学版),2010,30(01):40-42.

60.     袁伟燕,黄中伟,黄华,施公胜.大鼠重症急性胰腺炎脑损伤脑内核转录因子的表达[J].江苏医药,2008(01):73-74+112.DOI:10.19460/j.cnki.0253-3685.2008.01.028.

61.     沈雁波,黄中伟,唐建中,崔秋霞.喉罩通气在慢性阻塞性肺病重度呼吸衰竭病人的应用[J].江苏医药,2006(01):75.DOI:10.19460/j.cnki.0253-3685.2006.01.036.

62.     黄中伟,沈雁波,薛育政,陶然,黄介飞,孟宪镛.还原型谷胱甘肽对急性胰腺炎肝功能损害的治疗[J].中国急救医学,2005(12):922-923.

63.     黄中伟,唐建忠,陈瑜,袁鼎山,沈雁波,王伟.还原型谷胱甘肽对急性胰腺炎患者多脏器功能的保护作用[J].中国危重病急救医学,2005(11):39-40.

64.     沈雁波,黄中伟,唐建中,崔秋霞.喉罩通气在急诊心肺脑复苏的临床应用[J].南通大学学报(医学版),2005(04):281-282.

65.     黄中伟,唐建忠,袁鼎山,沈雁波,王伟,杨大明.还原型谷胱甘肽对急性胰腺炎全身炎症反应综合征的治疗作用[J].中华急诊医学杂志,2005(02):148-150.

部分著作主/参编著作

66.     参编《现代医院急诊管理》,2023.6,中国协和医科大学出版社.

67.     参编《急诊医学》,2022.6,人民卫生出版社.

68.     主编《急诊十年》,2013,南京大学出版社.

69.     参编《实用消化病诊疗学》,2006.9,世界图书出版社.

70.     参编《临床用药速查手册》, 2005.8,江苏科学技术出版社.

71.     参编《急性中毒诊疗规范》,2004.8,东南大学出版社.

72.     参编《实用消化病诊疗学》,2001.9,世界图书出版社.

 

主要科研项目

主持和参与多项省级及以上科研项目,曾获得省医院管理协会科研成果一等奖、省科技进步三等奖、省新技术引进二等奖等,获得国际、国家发明专利各一项,发布地方标准一项。

讲授课程

急诊医学、危重症医学、急诊临床思维与决策等

已毕业硕士生54名;在读博士生2名,硕士生6名。