姓名：丁伟峰
职称：副教授、副主任技师
个人简介：安徽安庆人，医学博士，硕导，美国德克萨斯大学访问学者。教育部学位论文评审专家、中国医药教育协会医学基因组学与生物信息学专委会委员、江苏省免疫学会转化医学专委会委员、江苏省医学会检验分会临床分子学组成员。江苏省“333工程”中青年科学技术带头人、江苏省青年医学重点人才、南通市“226工程”中青年科技领军人才、南通市医学重点人才。
专业研究领域：临床医学、临床检验诊断学、肿瘤表观遗传学。
主要专著与论集：
[1] Ding W, Pu W, Wang L, Jiang S, Zhou X, Tu W, Yu L, Zhang J, Guo S, Liu Q, Ma Y, Chen S, Wu W, Reveille J, Zou H, Jin L, Wang J. Genome-wide DNA methylation analysis in systemic sclerosis reveals hypomethylation of interferon-associated genes in CD4+ and CD8+ T cells. J Invest Dermatol., 2018, 138(5):1069-1077.
[2] Ding W, Pu W, Jiang S, Ma Y, Liu Q, Wu W, Chu H, Zou H, Jin L, Wang J, Zhou X. Evaluation of the antifibrotic potency by knocking down SPARC, CCR2 and SMAD3. EBioMedicine. 2018, 38:238-247.
[3] Shao K#, Pu W#, Zhang J#, Guo S, Qian F, Glurich I, Jin Q, Ma Y, Ju S, Zhang Z*, Ding W*. DNA hypermethylation contributes to colorectal cancer metastasis by regulating the binding of CEBPB and TFCP2 to the CPEB1 promoter. Clin Epigenet. 2021, 13(1): 89.
[4] Pu W#, Qian F#, Liu J, Shao K, Xiao F, Jin Q, Liu Q, Jiang S, Zhang R, Zhang J, Guo S, Zhang J, Ma Y*, Ju S*, Ding W*. Targeted Bisulfite Sequencing Reveals DNA Methylation Changes in Zinc Finger Family Genes Associated With KRAS Mutated Colorectal Cancer. Front Cell Dev Biol. 2021,9:759813.
[5] Ding W*, Ma Y, Zhu W, Pu W, Zhang J, Qian F, Zhou Y, Deng Y, Guo S, Wang J, Zhou X*. MICA *012:01 Allele Facilitates the Metastasis of KRAS-Mutant Colorectal Cancer. Frontiers in Genetics. 2020, 11:511.
[6] Ding W, Wang G, Shao K, Wang F, Huang H, Ju S, Cong H, Wang H. Amelioration of colorectal cancer using negative lipidoid nanoparticles to encapsulate siRNA against APRIL by enema delivery mode. Pathol Oncol Res. 2014;20(4):953-64.
[7] Ding W, Wang F, Zhang J, Guo Y, Ju S, Wang H. A novel local anti-colorectal cancer drug delivery system: negative lipidoid nanoparticles with a passive target via a size-dependent pattern. Nanotechnology. 2013, 24(37):375101.
主要科研项目
主持多项省部级以上科研项目，其中包括国家自然科学基金项目2项，中国博士后基金1项。
讲授课程
分子诊断学、临床生物化学检验等
指导研究生情况
已毕业硕士生2名；在读硕士生4名。
