姓名:桑爱民
职称:教授、二级主任医师、博士研究生导师
个人简介:江苏如东人,1986年毕业于南通医学院。
曾任南通大学医学院常务副院长、南通大学附属医院副院长、南通大学眼科学教研室副主任、拉萨市人民医院党委副书记、常务副院长。
现任南通大学循证医学中心副主任、教育部临床医学类教指委委员、教育部临床医学专业认证专家、教育部高等教育教学专家、中国医师协会毕教委评估工作委员会委员、中华医学会医学教育分会临床教学工作委员会委员、中华预防医学会循证预防专委会常委、中国医师协会循证医学分会循证眼科专委会委员、中国医药教育协会医学模拟教育专业委员会委员、中国医院协会模拟医学专业委员会委员、江苏省医学会理事、江苏省医师协会理事、江苏省医学会职业病学分会副主任委员、江苏省医师协会职业病学专委会副主任委员、南通市医保研究会眼科专业委员会主任委员。
苏州大学博士研究生导师、大连医科大学硕士研究生导师。
专业研究领域:眼底病、玻璃体视网膜疾病、眼外伤、职业性眼病。
专著与论集:
1. Effectiveness of Panretinal Photocoagulation Plus Intravitreal Anti-VEGF Treatment Against PRP Alone for Diabetic Retinopathy: A Systematic Review With Meta-Analysis(一区6.055;Front Endocrinol (Lausanne).)
2. Fruquintinibinhibits VEGF/VEGFR2 axis ofchoroidalendothelialcellsandM1-type macrophages to protect against mouse laser-induced choroidal neovascularization(一区9.0; Cell Death Dis.)
3. Geniposide alleviates choroidal neovascularization by downregulating HB EGF release from RPE cells by downregulating the miR-145-5p/NF-κB axis(二区3.77;Exp Eye Res. )
4. Brivanib, a multitargeted small‐molecule tyrosine kinase inhibitor, suppresses lase‐induced CNV in a mouse model of neovascular AMD(二区5.6;J Cell Physiol. )
5. Involvement of Fra-1 in Retinal Ganglion Cell Apoptosis in Rat LightInduced Retina Damage Model(二区4.0;Cell Mol Neurobiol. )
6. p21CIP/WAF1 saRNA inhibits proliferative vitreoretinopathy in a rabbit mode(三区3.7;PLoS One. )
7. Regulator of G-protein signaling 1 promotes choroidal neovascularization in age-related macular degeneration(三区3.616;Ann Transl Med.)
8. TNF-α released from retinal Müller cells aggravates retinal pigment epithelium cell apoptosis by upregulating mitophagy during diabetic retinopathy(三区3.1;Biochem Biophys Res Commun. )
9. Association between Retinal Vascular Geometric Changes and Cognitive Impairment: A Systematic Review and Meta-Analysis(三区3.077;J Clin Neurol. )
10. Computer aided diabetic retinopathy detection based on ophthalmic photography: a systematic review and Meta-analysis(三区1.4;nt J Ophthalmol. )
11. YAP via interacting with STAT3 regulates VEGF-induced angiogenesis in human retinal microvascular endothelial cells(三区3.7;Exp Cell Res. )
12. Tissue factor induces VEGF expression via activation of the Wnt/β-catenin signaling pathway in ARPE-19 cells.(三区2.367;Mol Vis.)
13. Inhibition of TBK1 reduces choroidal neovascularization in vitro and in vivo(三区3.1;Biochem Biophys Res Commun. )
14. PKR promotes choroidal neovascularization via upregulating the PI3K/Akt signaling pathway in VEGF expression(三区2.367;Mol Vis. )
15. Inhibition of RACK1 ameliorates choroidal neovascularization formation in vitro and in vivo(三区3.6;Exp Mol Pathol. )
16. Expression of RBMX in the light-induced damage of rat retina in vivo(三区4.0;Cell Mol Neurobiol. )
17. Up-Regulation of PKM2 Relates to Retinal Ganglion Cell Apoptosis After Light-Induced Retinal Damage in Adult Rats(三区4.0;Cell Mol Neurobiol. )
18. Efficacy and effectiveness of anti-VEGF or steroids monotherapy versus combination treatment for macular edema secondary to retinal vein occlusion: a systematic review and meta-analysis(四区2.0;BMC Ophthalmol. )
19. Andrographolide attenuates choroidal neovascularization by inhibiting the HIF-1α/VEGF signaling pathway.(四区3.1;Biochem Biophys Res Commun. )
20. Upregulation of SYF2 Relates to Retinal Ganglion Cell Apoptosis and Retinal Glia Cell Proliferation After Light-Induced Retinal Damage(四区3.1;J Mol Neurosci. )
21. Müller glia cells activation in rat retina after optic nerve injury: spatiotemporal correlation with transcription initiation factor IIb(四区3.1;J Mol Neurosci. )
22. Involvement of transcription initiation factor IIB in the light-induced death of rat retinal ganglion cells in vivo(四区3.2;J Mol Histol.)
23. Association of angiotensin-converting enzyme gene 2350 G/A polymorphism with diabetic retinopathy in Chinese Han population(四区2.8;Mol Biol Rep. )
24. Roles of Wnt/β-catenin signaling in retinal neuron-like differentiation of bone marrow mesenchymal stem cells from nonobese diabetic mice(四区3.1;J Mol Neurosci. )
25. Light-induced retinal ganglion cell damage in vivo involves Dexras1 (四区2.2;Mol Vis. )
《糖尿病性眼病》(主编)
《临床医学概论》(主编)
《基于器官系统的临床实习教程》(主编)
《循证医学基础与实践》(副主编)
《医学生临床实践技能培训教程》(副主编)
《生理学(案例版)》(副主编)
《住院医师规范化培训实用手册》(副主编)
《眼科学(案例版)》(第二版)(参编)
《眼科学(案例版)》(参编)
《青光眼手术学》(参编)
主要科研项目和成果
主持省部级以上科研项目15项,省级教改项目10余项。
主持首批国家一流本科课程《整合式 PBL 课程》。
获省市科技进步一等奖、二等奖,新技术引进奖5项。
获省级教学成果特等奖1项、一等奖1项、二等奖3项、三等奖1项。
讲授课程
眼科学、整合式PBL课程
指导研究生情况
已毕业硕士生20名;在读博士生3名,硕士生11名。
指导研究生获省优秀专业学位硕士学位毕业论文。