姓名：吕秀芳
职称：副教授
个人简介：黑龙江佳木斯人，理学博士。
专业研究领域：基础医学、肿瘤病理、肝癌发生发展分子机制。
专著与论集：
1. Lv XF, Zhang AQ, Liu WQ, Zhao M, Li J, He L, Cheng L, Sun YF, Qin G, et al. Liver injury changes the biological characters of serum small extracellular vesicles and reprograms hepatic macrophages in mice. World journal of gastroenterology 2021; 27(43): 7509-7529 [PMID: 34887646 PMCID: Pmc8613741 DOI: 10.3748/wjg.v27.i43.7509]
2. Zhao F, Cheng L, Shao Q, Chen Z, Lv X, Li J, He L, Sun Y, Ji Q, et al. Characterization of serum small extracellular vesicles and their small RNA contents across humans, rats, and mice. Scientific reports 2020; 10(1): 4197 [PMID: 32144372 PMCID: Pmc7060188 DOI: 10.1038/s41598-020-61098-9]
3. Dai W, Liu Y, Zhang Y, Sun Y, Sun C, Zhang Y, Lv X. Expression of neuropeptide Y is increased in an activated human HSC cell line. Scientific reports 2019; 9(1): 9500 [PMID: 31263154 DOI: 10.1038/s41598-019-45932-3]
4. Zhao F, Gong X, Liu A, Lv X, Hu B, Zhang H. Downregulation of Nedd4L predicts poor prognosis, promotes tumor growth and inhibits MAPK/ERK signal pathway in hepatocellular carcinoma. Biochemical and biophysical research communications 2018; 495(1): 1136-1143 [PMID: 29175326 DOI: 10.1016/j.bbrc.2017.11.139]
5. Lv X, Zhao F, Huo X, Tang W, Hu B, Gong X, Yang J, Shen Q, Qin W. Neuropeptide Y1 receptor inhibits cell growth through inactivating mitogen-activated protein kinase signal pathway in human hepatocellular carcinoma. Medical oncology (Northwood, London, England) 2016; 33(7): 70 [PMID: 27262566 DOI: 10.1007/s12032-016-0785-1]
6. Lv XF, Sun LL, Cui CL, Han JS. NAc Shell Arc/Arg3.1 Protein Mediates Reconsolidation of Morphine CPP by Increased GluR1 Cell Surface Expression: Activation of ERK-Coupled CREB is Required. The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2015 [PMID: 25746394 DOI: 10.1093/ijnp/pyv030]
7. Hu F, Deng X, Yang X, Jin H, Gu D, Lv X, Wang C, Zhang Y, Huo X, et al. Hypoxia upregulates Rab11-family interacting protein 4 through HIF-1alpha to promote the metastasis of hepatocellular carcinoma. Oncogene 2015 [PMID: 25745995 DOI: 10.1038/onc.2015.49]
8. Ge T, Shen Q, Wang N, Zhang Y, Ge Z, Chu W, Lv X, Zhao F, Zhao W, et al. Diagnostic values of alpha-fetoprotein, dickkopf-1, and osteopontin for hepatocellular carcinoma. Medical oncology (Northwood, London, England) 2015; 32(3): 59 [PMID: 25652109 DOI: 10.1007/s12032-014-0367-z]
9. 吕秀芳，胡宝英, 巩秀. 内侧前额叶皮层神经元可塑性改变在吗啡奖赏记忆形成中的作用. 中华行为与脑科学杂志 2014, 23(12):1061-1064.
10. Huang Y, Yang X, Zhao F, Shen Q, Wang Z, Lv X, Hu B, Yu B, Fan J, Qin W: Overexpression of Dickkopf-1 predicts poor prognosis for patients with hepatocellular carcinoma after orthotopic liver transplantation by promoting cancer metastasis and recurrence. Medical oncology (Northwood, London, England) 2014, 31(7):966.
主要科研项目
主持国家自然科学基金青年项目1项，中国博士后基金项目1项，南通市科技计划面上项目1项。
讲授课程
病理学
指导研究生情况
无
