姓名:季菊玲
职称:教授
个人简介:江苏南通人,医学博士。
专业研究领域:基础医学、肝脏免疫微环境与肝纤维化和肝细胞肝癌方面的研究。
专著与论集:
1. Lv XF, Zhang AQ, Liu WQ, Zhao M, Li J, He L, Cheng L, Sun YF, Qin G, Lu P, Ji YH, Ji JL. Liver injury changes the biological characters of serum small extracellular vesicles and reprograms hepatic macrophages in mice. World J Gastroenterol. 2021 Nov 21;27(43):7509-7529.
2. Zhao F, Cheng L, Shao Q, Chen Z, Lv X, Li J, He L, Sun Y, Ji Q, Lu P, Ji Y, Ji J. Characterization of serum small extracellular vesicles and their small RNA contents across humans, rats, and mice Sci Rep. 2020 Mar 6;10(1):4197.
3. Sun Y, Li W, Shen S, Yang X, Lu B, Zhang X, Lu P, Shen Y, Ji J. Loss of alanine-glyoxylate and serine-pyruvate aminotransferase expression accelerated the progression of hepatocellular carcinoma and predicted poor prognosis. J Transl Med. 2019 Nov 26;17(1):390.
4. Lu P, Yan M, He L, Li J, Ji Y, Ji J. Crosstalk between Epigenetic Modulations in Valproic Acid Deactivated Hepatic Stellate Cells: An Integrated Protein and miRNA Profiling Study. Int J Biol Sci. 2019 Jan 6;15(1):93-104.
5. Eggert T, Wolter K, Ji J, Ma C, Yevsa T, Klotz S, Medina-Echeverz J, Longerich T, Forgues M, Reisinger F, Heikenwalder M, Wang XW, Zender L, Greten TF. Distinct Functions of Senescence-Associated Immune Responses in Liver Tumor Surveillance and Tumor Progression. Cancer Cell, 2016,30(4),533-547.
6. Wang W, Yan M, Ji Q, Lu J, Ji Y, Ji J. Suberoylanilide hydroxamic acid suppresses hepatic stellate cells activation by HMGB1 dependent reduction of NF-κB1. PeerJ. 2015 Nov 3;3:e1362.
7. Ji J, Eggert T, Budhu A, Forgues M, Takai A, Dang H, Ye Q, Lee JS, Kim JH, Greten TF, Wang XW. Hepatic stellate cell and monocyte interaction contributes to poor prognosis in hepatocellular carcinoma. Hepatology. 2015 Aug;62(2):481-95. 7.
8. Ji Y, Zhang J, Wang W, Ji J. Functional study of miR-27a in human hepatic stellate cells by proteomic analysis: comprehensive view and a role in myogenic tans-differentiation. PLoS One. 2014 Sep 29;9(9):e108351.
9. Ji J, Yu F, Ji Q, Li Z, Wang K, Zhang J, Lu J, Chen L, E Q, Zeng Y, Ji Y. Comparative proteomic analysis of rat hepatic stellate cell activation: a comprehensive view and suppressed immune response. Hepatology. 2012 Jul;56(1):332-49.
10. Ji Y, Ji J, Sun F, Zeng Y, He X, Zhao J, Yu Y, Yu S, Wu W. Quantitative Proteomics Analysis of Chondrogenic Differentiation of C3H10T1/2 Mesenchymal Stem Cells by iTRAQ Labeling Coupled with On-line Two-dimensional LC/MS/MS, Molecular & Cellular Proteomics, 2010,9(3), 550-564.
11. Ji J, Zhang J, Huang G, Qian J, Wang X, Mei S. Over-expressed microRNA-27a and 27b influence fat accumulation and cell proliferation during rat hepatic stellate cell activation, FEBS Letters, 2009,583(4), 759-766.
主要科研项目
主持多项省部级以上科研项目,其中包括国家自然科学基金项目4项,含国际(地区)合作与交流项目NSFC-NIH项目(中美)1项。
讲授课程
病理学
指导研究生情况
已毕业博士生1名,硕士生11名;在读博士生3名,硕士生6名。