姓名：陈罡
职称：教授
个人简介：江苏南通人，医学硕士、理学博士。
专业研究领域：慢性疼痛、神经再生、干细胞。
专著与论集：
1. Zhao L*, Luo H*, Ma Y, Zhu SZ, Wu YJ, Lu MX, Yao XJ, Liu X, Chen G#. An analgesic peptide H-20 attenuates chronic pain via the PD-1 pathway with few adverse effects. PNAS, 2022, July 25, 119(31): e2204114119.
2. Zhang YH, Sang R, Bao JY, Jiang ZH, Qian DN, Zhou Y, Su WF, Wei JH, Zhao L, Wei ZY, Zhao YY, Shi MX, Chen G#. Schwann cell-derived CXCL2 contributes to cancer pain by modulating macrophage infiltration in a mouse breast cancer model. Brain, Behavior, and Immunity, 2023 Feb 6;109:308-320.
3. Pan JY, Zhao YY, Sang R, Yang RY, Bao JY, Wu YJ, Fei Y, Wu J, Chen G#. HAP1 inhibition contributes to neuropathic pain by suppressing Cav1.2 activity and attenuating inflammation. Pain. 2023 Jun 1;164(6):e286-e302.
4. Chen G#, Xu J, Luo H, Luo X, Singh SK, Ramirez JJ, James ML, Mathew JP, Berger M, Eroglu C#, Ji RR#. Hevin/ Sparcl1/ drives pathological pain through spinal cord astrocyte and NMDA receptor signaling. JCI Insight. 2022 Dec 8;7(23):e161028.
5. Wei JH*, Shang R*, Wang JQ, Zhu SZ, Yin JQ, Chen Y, Zhao YY, Chen G#.ACE2 overexpressing mesenchymal stem cells alleviates COVID-19 lung injury by inhibiting pyroptosis. iScience, 2022, Apr 15;25(4):104046.
6. Wei JH*, Su WF*, Zhao YY, Wei ZY, Hua YC, Xue P, Zhu X, Chen Y#, Chen G#. Maresin 1 promotes nerve regeneration and alleviates neuropathic pain after nerve injury. J Neuroinflammation. 2022,19:32.
7. Deng GC, Lu M, Zhao YY, Yuan Y, Chen G#. Activated spinal astrocytes contribute to the later phase of carrageenan-induced prostatitis pain. Journal of Neuroinflammation, 2019 Oct 25;16(1):189.
8. Su WF, Fan Wu, Jin ZH, Yun Gu, Chen YT, Fei Y, Chen H, Wang YX, Xing LY, Zhao YY, Yuan Y, Tang X, Chen G#. Overexpression of P2X4 receptor in Schwann cells promotes motor and sensory functional recovery and remyelination via BDNF secretion after nerve injury. Glia, 2019, 67(1): 78–90.
9. Chen G, Zhang YQ, Qadri YJ, Serhan CN, Ji RR#. Microglia in Pain: Detrimental and protective roles in the pathogenesis and resolution of pain. Neuron, 2018,100 (6): 1292-1311.
10. Chen G*, Kim YH*, Li H, Luo H, Liu DL, Zhang ZJ, Lay M, Chang W, Zhang YQ#, Ji RR#. PD-L1 inhibits acute and chronic pain by suppressing nociceptive neuron activity via PD-1.Nature Neuroscience.2017, 20(7):917-926.
主要科研项目
主持多项省部级以上科研项目，其中包括国家自然科学基金项目5项，国家重点研发计划子课题1项、江苏省重点研发计划1项。
讲授课程
组织学与胚胎学、再生医学、神经生物学
指导研究生情况
已毕业博士生1名，硕士生12名；在读博士生3名，硕士生6名。
