姓名：郑文杰
职称：副研究员
个人简介：医学博士，维克森林大学访问学者，中华医学会航海医学分会表型组学专委会委员、中国抗癌协会整合肿瘤学分会青年委员。入选省“333高层次人才”，获得省科学技术奖三等奖及省医学新技术引进一等奖
专业研究领域：基础医学，临床医学，肿瘤学，肝脏炎癌转化病理
专著与论集：
1.Bian S, Ni W, Zhou L, et al. Ubiquitin-specific protease 1 facilitates hepatocellular carcinoma progression by modulating mitochondrial fission and metabolic reprogramming via cyclin-dependent kinase 5 stabilization. Cell Death Differ. 2024 Sep;31(9):1202-1218.
2.Dai C, Tong Y, Bai N, et al. Decoding the role of nucleic acid binding protein 2 in lipid dysregulation and hepatocellular carcinoma progression through LKB1-mediated mitochondrial dysfunction. Cell Signal. 2025 Aug;132:111820.
3.Bian S, Ni W, Zhu M, et al. Flap endonuclease 1 Facilitated Hepatocellular Carcinoma Progression by Enhancing USP7/MDM2-mediated P53 Inactivation. Int J Biol Sci. 2022 Jan 1;18(3):1022-1038.
4.Ni W, Lin S, Bian S, et al. Biological testing of chitosan-collagen-based porous scaffolds loaded with PLGA/Triamcinolone microspheres for ameliorating endoscopic dissection-related stenosis in oesophagus. Cell Prolif. 2021 Mar;54(3):e13004.
5.Zhu M, Wu M, Bian S, et al. DNA primase subunit 1 deteriorated progression of hepatocellular carcinoma by activating AKT/mTOR signaling and UBE2C-mediated P53 ubiquitination. Cell Biosci. 2021 Feb 23;11(1):42.
6.Zhang J, Wang L, Song Q, et al. Organoids in recapitulating tumorigenesis driven by risk factors: Current trends and future perspectives. Int J Biol Sci. 2022 Mar 28;18(7):2729-2743.
主要科研项目：近年主持多项省部级以上科研项目，其中包括国家自然科学基金项目3项，江苏省重点研发计划1项。
讲授课程：诊断学
指导研究生情况
近3年指导基础医学及临床医学硕士研究生6人，博士研究生1人。
